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The Link Between Genetics And Colon Cancer

Jun 26, 2008
Genetic drift , selection , migration, etc., are parameters which are used to construct models that allow us to generate predictions and obtain deeper insight.

The discovery of DNA and the elucidation of the biophysical substrate which constrains the modes of inheritance in a concrete manner opened up the startling vistas of molecular evolutionary genetics. Generally, gene mutations can disrupt an entire protein, but in colon cancers, only half the APC protein is lost, while the other half remains, Ahmed explains. Her work in fruit flies suggests a reason for this unexplained phenomenon.

Genes, such as Notch 3, were affected by the stage of tumorigenesis. After pathway analyses, many genes were identified that were over-represented for their respective biological processes (genes involved in the metabolism of carbohydrates and lipids, ion transport and signaling pathways).

Colon cancer is very rare in people under 30 years of age. Most people diagnosed with the disease are in their 50?s or 60?s. Colon cancer is one of the most common forms of cancer in the United States for both men and women. Also referred to as colorectal cancer, colon cancer occurs in the large intestine (colon) or the rectum (end of the colon).

Colon cancer is the second-leading cause of cancer deaths. The best way to detect colon cancer is with a colonoscopy, a screening exam that involves inserting a flexible, lighted tube through the rectum up to the colon and viewing images on a monitor.

Colon cancer is often fatal if the cancer cells have spread unchecked through the lymphatic system or bloodstream to adjacent and/or distant tissues. Colorectal cancer has a strong tendency to metastasize to the liver, which represents the leading cause of death for people with the disease.

Colon cancer is preventable. The most important step towards preventing colon cancer is getting a screening test. Colon cancer is caused by the abnormal growth of cells in the lining of the bowel. Usually small lumps called polyps begin to form.

Generally, the less the olive oil is handled, the closer to its natural state and the better it is. Generally, the deeper a tumor has penetrated the bowel wall, the more difficult it is to cure with surgery alone. Generally, digestive diseases have been considered by psychiatry to result from anger turned inward.

It is now known that normal people's immune systems are able to recognize and destroy tiny cancer cells before they can spread. In the diseased or depressed person, the immune system does not function efficiently and may allow cancer to start.

Screening works because colon cancer is usually a slow-growing disease that starts with adenomatous polyps, small, protuberant growths inside the colon that may contain precancerous cells.

Screening tests are designed to find these polyps so doctors can remove them before they become cancerous. Screening saves lives.".Here are some myths about colon cancer and the facts patients need to know. Myth: Colon cancer only affects men Colon cancer affects both men and women, in fact approximately 26,000 women die every year from colon cancer.
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