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Anti-Estrogens vs. Anti-Aromatase: What They Are and When to Take Them

Sep 9, 2008
Anti-estrogens - these are used for blocking receptor sites, not to stop conversion of aas to estrogen. When it is already converted, anti-estrogens keep the body from performing this action. The anti-estrogens need to be taken before and at the first sign of receptor activity (gynecomastia), or to supplement with an aromatase inhibitor

nolvadex is most accurate example of an anti-estrogen. It binds itself to estrogen receptors, and in doing so blocks the ability of estrogen to be attached to such areas of the body, such as the breast and testes. This compound is essential to yielding wanted results. Nolvadex has been used to treat breast cancer for years in those whose circulating levels of estrogen are too high to support the shrinking of tumors caused by estrogen. There are possiblities to reverse the actions of an existing growth process of diseased tissue and prevent further growth. Those who are already showing signs of gynecomastia should take nolvadex. It's important to not confuse nolvadex and arimidex (see below) these are usually grouped together as the same kind of drug, but are not. Nolvadex, again, doesn't prevent aromatization but will act as an estrogen antagonist. This won't prevent testosterone from converting, but struggles with them for receptor position.

Anti-aromatase - used to block the conversion of aromatizing aas to estrogen, and through binding to the enzyme aromatase, can block the production of estrogens in the body. Bodybuilders everywhere are using this class of drugs during cycles with particular steroids, this will avoid any mishaps to prevent any undesirable hormonal activity. Before any symptoms of aromatization have occurred at the beginning of a cycle, take anti-aromatase.

Arimidex often gets confused with an anti-estrogen, but in actuality is an aromatase inhibitor. This is necessary to use when using massive amounts of aromatizing aas, or when prone to developing gynecomastia and using average amounts of aas. Overall, also true with all aromatase inhibitors, the mechanism of action is to block the conversion of aromatizable steroids to estrogen. This is quite opposite to the mechanism and action of an anti-estrogen, such as clomid or nolvadex, which are basically in place to block estrogen receptors in some tissues, such as the breast tissue and area of the testes. Usually if you are using arimidex, you aren't using clomid, but doing so may have beneficial results.

Arimidex fortunately does not contain the side effects of a lot of aromatase inhibitors, such as cytadren or others, a high degree of estrogen blocking will also be developed. Testing should always take place because it is possible to reduce estrogen too much with arimidex.

However, costing about $7 -$9 per milligram makes this newer aromatase inhibitor reasonably expensive.

Synthetic estrogens - used to jump-start a person's individual sex hormones by influencing the hypothalamohypophysial testicular axis which releases more gonadotropin in order for rapid release of fsh and lh. To kickstart your own hormonal assay use these post cycle.

Clomid is often grouped with anti-estrogens or anti-aromatase/ aromatase inhibiting drugs, it is however very different. This is a synthetic estrogen which belongs to the group of sex hormones, as nolvadex does. When the body's own testosterone production is slowed down because of aas, clomid is effective. This is the reason that most take clomid once steroids have been discontinued. Restoring normal levels of testosterone as quickly as possible is important so that losses of muscle mass and strength is as low as possible. Hcg is a great combination for clomid and can offer even greater results. The anti-estrogenic effects of clomid are lower than those found in proviron and teslac, it is mainly taken as a testosterone stimulant (via gonadotropin stimulating effects).
About the Author
Dane Fletcher is the world-wide authority on bodybuilding and steroids. He has coached countless athletes all over the world. To read more of his work, please visit either www.BodybuildingToday.com or www.SteroidsToday.com
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