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Resveratrol content in brief
Resveratrol is a phytoalexin produced naturally by several plants when under attack by pathogens such as bacteria or fungi. Resveratrol has many anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol is very well known in Western Europe as it can slow down the aging process. Resveratrol is found in the skin of red grapes and is a constituent of red wine. A total amount of Resveratrol per serving of wine (a 5-ounce glass) for white wines is found to be between 0.01 to 0.27 mg.
It exists as two geometric isomers: cis (Z) and trans (E), with cis-isomer. The trans form can undergo isomerisation to the cis form when exposed to ultraviolet irradiation.
Trans-resveratrol in the powder form was found to be stable under "accelerated stability" conditions of 75% humidity and 40 degrees C in the presence of air. Resveratrol content also stayed stable in the skins of grapes and pomace taken after fermentation and stored for a long period. All that means is that That resveratrol can have two forms of existence according to the subject.
They appear to mimic several of the biochemical effects of calorie restriction. Even in the life cells it triggers the production of SIRT1 which is required by the cells to stay young. A new report indicates that resveratrol activates Sirtuin 1 (SIRT1) and PGC-1a and improves functioning of the mitochondria. Another research calls into question the theory connecting resveratrol, SIRT1, and calorie restriction.
Resveratrol content has proved to be especially beneficial in the case of cancer cells. Resveratrol content interferes with all three stages of carcinogenesis" initiation, promotion and progression. Resveratrol straightaway attacks the energy source of the carcinogenic cells, mitochondria, thus stopping them from multiplying.
Resveratrol content was reported effective at neuronal cell dysfunction and cell death, and in theory could help against diseases such as Huntington's disease and Alzheimer's disease. Again, this has not yet been tested in humans for any disease.
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